Waggoner Lab on X: "Cryopyrin-associated periodic syndrome (CAPS) NLRP3 variants form constitutively active inflammasomes inducing pyroptosis & IL-18 release without cell priming, contributing to autoinflammatory flares while metabolically limiting IL ...
IJMS | Free Full-Text | The NLRP3 Inflammasome: Relevance in Solid Organ Transplantation
Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype - Journal of Allergy and Clinical Immunology
www.frontiersin.org/files/Articles/618231/fimmu-11...
NLRP3-associated autoinflammatory diseases: Phenotypic and molecular characteristics of germline versus somatic mutations - ScienceDirect
Spotlight on the NLRP3 inflammasome pathway | JIR
PKA-mediated NLRP3 inhibition pathway and the relevant CAPS mutations.... | Download Scientific Diagram
Investigating the Role of NLRP3 Inflammasome and Immunometabolism in CAPS Patients - Medriva
Clinical manifestations of NLRP3 spectrum disease. CAPS,... | Download Scientific Diagram
Targeting the NLRP3 inflammasome in inflammatory diseases | Nature Reviews Drug Discovery
The NLRP3 inflammasome: contributions to inflammation-related diseases | Cellular & Molecular Biology Letters | Full Text
The NLRP3 inflammasome: molecular activation and regulation to therapeutics | Nature Reviews Immunology
Spotlight on the NLRP3 inflammasome pathway | JIR
The NLRP3 inflammasome: contributions to inflammation-related diseases | Cellular & Molecular Biology Letters | Full Text
PKD-mediated NLRP3 activation pathway and the relevant CAPS mutations.... | Download Scientific Diagram
NLRP3 inflammasome sensor | Review | Invivogen
NLRP3 - Ventus Therapeutics
NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation - ScienceDirect
NLRP3 CAPS mutations and model of NEK7-mediated NLRP3 inflammasome... | Download Scientific Diagram
INFLAMMASOME INHIBITORS - 21st Century Miracle Drugs: Spotlight on Clinical NLRP3 Inflammasome Inhibitors
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production | Nature Communications
Frontiers | The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases
An update on the regulatory mechanisms of NLRP3 inflammasome activation | Cellular & Molecular Immunology
Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | eLife
CAPS and NLRP3 | Journal of Clinical Immunology
NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma - McKee - 2020 - Journal of Leukocyte Biology - Wiley Online Library
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice | EMBO reports
IJMS | Free Full-Text | The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
Targeting the NLRP3 Inflammasome via BTK | Semantic Scholar
