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Waggoner Lab on X: "Cryopyrin-associated periodic syndrome (CAPS) NLRP3 variants form constitutively active inflammasomes inducing pyroptosis & IL-18 release without cell priming, contributing to autoinflammatory flares while metabolically limiting IL ...
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Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype - Journal of Allergy and Clinical Immunology
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The NLRP3 inflammasome: contributions to inflammation-related diseases | Cellular & Molecular Biology Letters | Full Text
PKD-mediated NLRP3 activation pathway and the relevant CAPS mutations.... | Download Scientific Diagram
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